Cardiac function after cardiac arrest: what do we know?

نویسندگان

چکیده

Postcardiac arrest myocardial dysfunction (PCAMD) is a frequent complication faced during post-resuscitation care that adversely impacts survival and neurological outcome. Both mechanical electrical factors contribute to the occurrence of PCAMD. Prearrest ventricular function, cause cardiac arrest, global ischemia, resuscitation factors, ischemia/reperfusion injury treatments severity PCMAD. The pathophysiology PCAMD complex include myocytes energy failure, impaired contractility, edema, mitochondrial damage, activation inflammatory pathways coagulation cascade, persistent ischemic stiffness. Hypotension low output with vasopressor/inotropes need are after resuscitation. However, clinical, hemodynamic laboratory signs shock frequently altered by treatment, potentially being misleading not fully reflecting postcardiac syndrome. Even if validated criteria lacking, an extensive evaluation useful define benign malign form circulatory shock, having treatment prognostic implications. Cardiac decreased particularly in patients treated target temperature management (TTM); however, it independently associated Sinus bradycardia TTM seems good outcome, representing promising indicator. Higher mean arterial pressure (MAP) be improved cerebral function arrest; two recent randomized clinical trials failed replicate these results. Recommendations on optimization relatively poor largely based general principle intensive medicine.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Superior Capsule Reconstruction: What Do We Know?

The management of irreparable rotator cuff tears remains challenging. Since its introduction by Mihata in 2012, superiorcapsule reconstruction (SCR) has grown in popularity at an astonishingly rapid rate. The aim of this article is to providea comprehensive review of the available literature, in order to highlight what has so far been published on SCR,covering all aspects including biomechanica...

متن کامل

Extracorporeal membrane oxygenation after cardiac arrest in children: what do we know?

The use of extracorporeal membrane oxygenation (ECMO) as a resuscitative measure during or after manual cardiopulmonary resuscitation (CPR) shows sharply contrasting results. To assess the added value of ECMO in this situation and looking for predictors of mortality we performed a meta-analysis of individual patients collected from observational studies. An electronic Pubmed search restricted t...

متن کامل

Molecular approaches to diagnosis of invasive aspergillosis what we know and what we do not know.

Invasive aspergillosis (IA) are a major complication in immunocompromized patients where can be serious and rapidly fatal. Early diagnosis and early appropriate antifungal treatment is important in reducing mortality and morbidity. But despite many efforts to develop detection methods, the diagnosis of IA still remains challenging and current conventional methods are limited for adequate diagno...

متن کامل

Hypothermic cardiac arrest in the homeless: what can we do?

Accidental deep hypothermia with body temperature < 28 degrees C induces high mortality rates for neurological and cardiac complications. Although several reports described successful treatment of hypothermic arrest by extracorporeal membrane oxygenation (ECMO), the field of warming in the homeless is almost completely unquestioned although the malnutrition and the co-morbidities are usually be...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Minerva Anestesiologica

سال: 2021

ISSN: ['0375-9393', '1827-1596']

DOI: https://doi.org/10.23736/s0375-9393.20.14574-7